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Several recommendations on how to treat people at home with COVID-19 with mild to moderate symptoms have been proposed, starting with the use of anti-inflammatory drugs. The main recommended NSAIDs ...


Synthetic corticosteroids are widely available medications used to treat chronic inflammatory and autoimmune diseases. Systemic corticosteroids for COVID-19 management Based on evidence from pre ...


Prior observational studies have suggested that Aspirin ( Acetylsalicylic acid ) use may be associated with reduced mortality in high-risk hospitalized patients with COVID-19, but Aspirin’s efficacy i ...


There are few data comparing the relative effectiveness of the individual β-lactams. The objective of the study was to quantify the reduced effectiveness, defined as switching to a different antibi ...


Acetylsalicylic acid ( Aspirin ) is commonly used for primary and secondary prevention of cardiovascular diseases. Aspirin use is associated with better outcomes among COVID-19 positive patients. ...


Fluoroquinolones, one of the most commonly prescribed antibiotic classes, have been implicated in cases of central nervous system ( CNS ) and peripheral nervous system ( PNS ) adverse events, which hi ...


Fluoroquinolones are known to be accompanied by significant risks. However, the incidence of adverse events resulting in unplanned drug discontinuation when used for periprosthetic joint infections ( ...


Safety and final efficacy results from the pivotal phase 3 trial of BNT162b2, the mRNA-based COVID-19 vaccine candidate, were published in The New England Journal of Medicine ( NEJM ). In the trial ...


The medium-term effects of Coronavirus disease ( COVID-19 ) on multiple organ health, exercise capacity, cognition, quality of life and mental health are poorly understood. Fifty-eight COVID-19 pa ...


In the absence of effective vaccines and with limited therapeutic options, convalescent plasma is being collected across the globe for potential transfusion to coronavirus disease 2019 ( COVID-19 ) pa ...


Concerns over the safety of non-steroidal anti-inflammatory drug ( NSAID ) use during severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) infection have been raised. Researchers have stud ...


Prolonged symptom duration and disability are common in adults hospitalized with severe coronavirus disease 2019 ( COVID-19 ). Characterizing return to baseline health among outpatients with milder ...


Initial preliminary findings from the Papa Giovanni XXIII Hospital sponsored SISCO ( Siltuximab In Serious COVID-19 ) Study, based on a pre-planned data analysis on 24 March 2020, were presented. S ...


The results of a study has shown that patients living with HIV and one of a variety of potentially deadly cancers could be safely treated with the immunotherapy drug Pembrolizumab ( Keytruda ). The ...


Data from clinical studies confirm the efficacy of switching to Dolutegravir ( DTG ) plus Rilpivirine ( RPV ) ( Juluca ) in selected patients. The primary objective of the study was to report the 9 ...